L-deprenyl plus L-phenylalanine
in the treatment of depression

by
Birkmayer W, Riederer P, Linauer W, Knoll J
J Neural Transm 1984; 59(1):81-7


ABSTRACT

The antidepressive efficacy of 1-deprenyl (5-10 mg daily) plus 1-phenylalanine (250 mg/day) has been evaluated in 155 unipolar depressed patients. Both oral and intravenous administration showed beneficial effects in 90% of outpatients and 80.5% of inpatients. It is concluded that this combined treatment has a potent antidepressive action based on the accumulation of 1-phenylethylamine in the brain.

PEA
High-dosage
Antidepressant
Atypical depressives
Selegiline and nitric oxide
Selegiline / neuroprotection
Selegiline and life-expectancy


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