Selegiline hydrochloride and cognition
by
Lees AJ
Department of Neurology,
Middlesex Hospital, London, UK.
Acta Neurol Scand Suppl 1991; 136:91-4

ABSTRACT

Selegiline HCl, 10 mg per day has been reported to improve attention and episodic memory in Parkinson's disease and early Alzheimer's disease. Selegiline also improves motor reaction times in Parkinson's and subjective feelings of increased vitality, euphoria and energy. At doses of between 10 and 40 mg a day it has also been shown to improve depression particularly when psychomotor retardation is prominent and anxiety minimal.

Structure
Metabolites
Interactions
Phenylethylamine
Desmethylselegiline
Selegiline and the DAT
Selegiline and nitric oxide
Selegiline and life-expectancy
Selegiline for longer-lived flies
Selegiline as an immunostimulant
Selegiline for cocaine-dependence
Selegiline and Parkinson's disease
Selegiline, NO and Alzheimer's disease

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